Feldene - the drug used for treatment of inflammatory and degenerative diseases of musculo-skeletal system. NSAIDS, renders antiinflammatory, analgestic, antiaggregant and febrifugal action. Not selectively suppresses COX1 and COX2. The analgetic effect is observed in 30 min. after peroral intake, the antiinflammatory effect occurs by the end of the 1 (first) week of treatment by Feldene. After a single dose of Feldene it acts during 24 h.
The drug is a prodrug and is activated in the acidic environment of the secretory tubules in the parietal cells. It reduces basal and stimulated secretion regardless of the nature of the stimulus. Prescribed in case of erosive ulcerative diseases of the gastrointestinal tract and eradication of Helicobacter pylori in infected patients with gastric and duodenal ulcer.