Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.
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Exforge product description
Exforge is a complex double-acting drug that contains 2 mutually interdependent basic substances. The first is a derivative of the dihydropyridine called amlodipine, which acts by plugging slow calcium channels. The second, named valsartan, causes competitive suppression of AT1 angiotensin II receptors. Both basic components correlate with each other. It is proved that in a complex they demonstrate more efficacy than it is shown in cases of monotherapy with a help of amlodipine or valsartan. Exforge is designed for the combined medical care of patients who suffer from a high blood pressure.
Exforge safety information
The pills of this pharmaceutical are swallowed regardless of the food intake, 1 time per day. The dosage depends upon the indicator of arterial pressure in the patient and the individual tolerability of the remedy. Exforge is not received to treat children, within pregnancy and breastfeeding. Exforge must not be assigned to treat patients with individual intolerance to valsartan, amlodipine, or any of the auxiliary components. Exforge is not prescribed for patients who have recently undergone renal transplantation or suffered from stenosis of the renal arteries. Patients experiencing the impaired hepatic function, hypertrophic obstructive cardiomyopathy, obstruction of the biliary tract, renal disorders, stenosis of an aorta, mitral stenosis, hyponatremia require additional medical care when using this combined drug.
Overdose
There were no reports of an overdosage by Exforge. Theoretically, there appears the likelihood of development of hypotension, dizziness, reflex tachycardia, shock. Swallowing a large number of pills by mistake, you must induce vomiting, clean the stomach, take sorbents. The proper patient's position in case of the overdose and development of hypotension to lie with raised legs. The healthcare specialist may prescribe a vasoconstrictor preparation, ask to take calcium gluconate as the hemodialysis is ineffective.
Exforge side effects
The reception of Exforge pills can be accompanied by nasopharyngitis, constipation, flu-like conditions, cough, exanthema, headache, paresthesia, dizziness, erythema, epigastric pain, sore throat, hyperhidrosis, muscle spasms, visual impairment, drowsiness, nausea, tachycardia, itching, facial pastness hyperglycemia, hyperplasia of the mucous gums, arthralgia, erythema multiforme, dry mouth, tinnitus, gastritis, laryngeal spasm, orthostatic dizziness, anxiety, polyuria, angioedema edema, pancreatitis, diarrhea, hot flashes, swelling of the joints, vasculitis, erectile dysfunction, hepatitis, a feeling of heaviness, gynecomastia, back pain, rhinitis, urticaria, thrombocytopenia, alopecia, peripheral edema, dyspnea, leukopenia, asthenic conditions, pollakuria, increased angina, pulmonary edema, mood lability, rhythm disturbances, insomnia, sinusitis, increased creatinine levels, neutropenia, peripheral neuritis pathology, anaphylaxis.
Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
ED Trial Pack (2 Viagra + 2 Cialis + 2 Levitra) - a trial set consists of six tablets, for those who want to understand what medicine is better for him. Includes 6 tablets (by 2 pсs.): Viagra, Cialis and Levitra. It can be taken by people older than 18 years, in case of problems in private life related to fatigue, stress, sleep debt, slow-moving way of life and abuse of addictions.
Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
A blocker of H1-histamine receptors of the first generation, derived from ethanolamine; eliminates the effects of histamine, mediated through this type of receptors. Promotes the local anaesthesia (when intaken, there is a short numbing of the mucous membranes in the mouth) - only in high doses, it blocks m-cholinergic receptors in the central nervous system, has sedative, hypnotic, antiemetic and antiparkinsonian effects. The therapeutic indications include: allergic conjunctivitis, allergic rhinitis, chronic urticaria, pruritic dermatoses, dermatographism, serum sickness.
Vantin - combined preparation, based simultaneously on 2 active substances: Cefpodoxime Proxetil. It belongs to the third generation of cephalosporins. Used to treat acute otitis media, tonsilitis, pharyngitis, respiratory tract infections, such as pulmonary pneumonia and chronic bronchitis.
Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) enzyme, which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and effective inhibitor of cyclic guanosine monophosphate (cGMP) type 5 (PDE5) phosphodiesterase enzyme in the corpus cavernosum that induces pulmonary vascular smooth muscle cell relaxation. It replenishes reduced erectile capacity by raising blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.
ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below: