The drug Malegra (Malegra DXT) contains two active substances in one pill: Sildenafil citrate 100 mg (as in a conventional tablet of Viagra) and Duloxetine, belonging to selective serotonin and norepinephrine reuptake inhibitors. The latter was invented by Eli Lilly and has long been used to prevent premature ejaculation. This is the latest drug that helps to treat erectile dysfunction. This medicine does not have an adverse effect on the cardiovascular system. The biggest advantage of this drug is its safety. Duloxetine gives the maximum effect together with Sildenafil citrate.
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Product Description
Malegra is a perfect solution for men with erectile dysfunction. A unique combination of two active components stimulates a stable erection. The first ingredient Sildenafil Citrate is famous for its efficiency in the treatment of men’s inability to erect and preserve an erection for some time. The second component Duloxetine is a perfect assistant because it’s aimed to relax muscles. The drug usually copes with nervousness and depression.
When a person takes the combination of these two drugs, he can easily relax and erect. Such a successful combination relaxes blood vessels and directs the bloodstream to the required areas (the pelvic and penile ones). The created pressure of blood makes the man’s genital rise and remains hard for up to six hours. The drug doesn’t prevent the process of semen ejection from the body at the moment of sexual climax. Still, it helps not to ejaculate too early.
Medics prescribe the pills in case of:
- Erection problems
- Premature ejaculation
- Impotence
- Sexual inability provoked by stress and chronic exhaustion
- Inability to have long sexual intercourse
Safety Information
A patient should agree on the treatment with a doctor and get the drug if it fits his health condition. If a man has some health problems which can contradict the treatment or even worsen his health state, it’s better to refuse from the pills intake. Medics do not recommend this drug to men who have:
- Liver dysfunction
- Kidney pathology
- Increased sugar in the blood
- Diabetes
- High blood pressure
- Experienced heart attack and stroke
- A condition of increased pressure within the eyeball, causing a gradual loss of sight
- Serious heart diseases
- Intolerance to the components of the pills
- Cancer
The drug can be used by males only. A person mustn’t take more than 1 pill a day because in case of the overdose he may feel sick and dizzy, vomit, suffer a headache, be nervous and experience indifference to everything that surrounds him.
The manual instruction is not to be neglected as well. Medics say that a person often suffers unwished reaction to the drug because of improper pills intake. It’s especially important to pay attention to the fact that a person should avoid fatty meals and alcoholic drinks during the medication. Coffee and grapefruit juice can also affect the organism badly when they are combined with the drug.
Side Effects
A man should turn to a health adviser to find out whether he can take the pills or not. According to the statistic, adverse effect of Sildenafil and Duloxetine combination doesn’t differ much from the side effects of other erectile dysfunction drugs. They are usually connected with the cardiovascular system but can also impair other organs. A man may have a headache, flushing of the face, inability to see distinctly, stuffiness in the nose, pain in the stomach, stomach upset or sickness. When a person is inclined to have hypertension or increased level of glucose in the blood, he may experience them after the drug consumption as well.
Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
ED Trial Pack (2 Viagra + 2 Cialis + 2 Levitra) - a trial set consists of six tablets, for those who want to understand what medicine is better for him. Includes 6 tablets (by 2 pсs.): Viagra, Cialis and Levitra. It can be taken by people older than 18 years, in case of problems in private life related to fatigue, stress, sleep debt, slow-moving way of life and abuse of addictions.
Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.
Ampicillin - Semi-synthetic penicillin, which has a wide range of effects and exhibits bactericidal effect. Suppresses the synthesis of the cell wall of bacteria: Streptococcus pneumoniae, Staphylococcus spp., Bacillus anthracis, Clostridium spp., Enterococcus faecalis, Listeria spp., Haemophilus influenzae, Neisseria meningitidis, Proteus mirabilis, Pasteurella multocida, Salmonella spp., Shigella spp., Escherichia coli, Aerobic non-spore-forming bacteria. Acid-resistant.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
Diltiazem - has anti-anginal, antiarrhytmic and hypotensive effects. Reduces the intracellular maintenance of Ca2+ in cardiomyocytes and cells of smooth muscles of blood vessels, reduces heart rate, shows insignificant negative inotropic effect, improves a coronary, brain and renal blood flow.
Ditropan - the antispasmodic, eliminates spasms and lowers a tone of unstriated muscles: GIT, biliary tract, uterus, debilitates detruzor. Increases bladder capacity, reduces the frequency of reductions of a detruzor, constrains desires to urination. It is well tolerated by patients at long prescription. It is taken at a neurogenic bladder, an urine incontience, night enuresis at children.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Eulexin - antineoplastic medicine, anti-androgen. Competitively blocks interaction of androgens with their cellular receptors; interferes with manifestation of biological effects of male sex hormones in androgensensetive organs. It is taken for palliative treatment of cancer.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.
An antidepressant used in cases of deep depression, panic disorders, social anxiety disorders, anxiety disorders. The mechanism of its action is based on the ability to selectively block the reuptake of serotonin by the presynaptic membrane of the neurons of the brain. Consequently, its serotonergic effect in the central nervous system that is responsible for the development of antidepressant effect, increases, which determines the effectiveness in the treatment of panic and social anxiety disorder.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
A blocker of H1-histamine receptors of the first generation, derived from ethanolamine; eliminates the effects of histamine, mediated through this type of receptors. Promotes the local anaesthesia (when intaken, there is a short numbing of the mucous membranes in the mouth) - only in high doses, it blocks m-cholinergic receptors in the central nervous system, has sedative, hypnotic, antiemetic and antiparkinsonian effects. The therapeutic indications include: allergic conjunctivitis, allergic rhinitis, chronic urticaria, pruritic dermatoses, dermatographism, serum sickness.
Prograf The active ingredient of the drug (Tacrolimus) binds to cytosolic protein (FKBP12), responsible for the intracellular accumulation of the drug. Designed for the prevention and treatment of allograft liver, kidneys and heart rejection reactions, including those resistant to standard immunosuppressive therapy regimes.
Seroquel - treats acute and chronic psychoses, including schizophrenia. The drug is also prescribed to patients with manic episodes associated with bipolar disorders.
Vantin - combined preparation, based simultaneously on 2 active substances: Cefpodoxime Proxetil. It belongs to the third generation of cephalosporins. Used to treat acute otitis media, tonsilitis, pharyngitis, respiratory tract infections, such as pulmonary pneumonia and chronic bronchitis.
Zestril is an angiotensin-converting enzyme inhibitor (ACE). It works by relaxing the blood vessels. This helps lower blood pressure. It is used in the treatment of high blood pressure, alone or in conjunction with other medicines.
Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) enzyme, which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and effective inhibitor of cyclic guanosine monophosphate (cGMP) type 5 (PDE5) phosphodiesterase enzyme in the corpus cavernosum that induces pulmonary vascular smooth muscle cell relaxation. It replenishes reduced erectile capacity by raising blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.
ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below: