It is a sulfonamide diuretic that is pharmacologically related to thiazide diuretics. The medicine inhibits sodium reabsorption in the cortical segment of the kidneys. It increases the excretion of sodium and chlorides in the urine and the excretion of potassium and magnesium, thus increasing diuresis. The antihypertensive effect of the active components appears at doses at which the diuretic effect is insignificant. Moreover, its antihypertensive effect persists even in patients with hypertension.
| Package | Per pill | Total price | Save | Order |
|---|---|---|---|---|
| 2.5 x 30 Pills | $1.94 | $58.28 + Bonus - 4 Pills | - | Add to cart |
| 2.5 x 60 Pills | $1.37 | $82.22 + Bonus - 4 Pills | $34.20 | Add to cart |
| 2.5 x 90 Pills | $1.18 | $106.17 + Bonus - 7 Pills | $68.40 | Add to cart |
| 2.5 x 120 Pills | $1.08 | $130.11 + Bonus - 7 Pills | $103.20 | Add to cart |
| 2.5 x 180 Pills | $0.99 | $178.01 + Bonus - 11 Pills | $171.00 | Add to cart |
| 2.5 x 270 Pills | $0.93 | $249.85 + Bonus - 11 Pills Free Trackable Delivery | $272.70 | Add to cart |
| 2.5 x 360 Pills | $0.89 | $321.69 + Bonus - 11 Pills Free Trackable Delivery | $378.00 | Add to cart |
| Package | Per pill | Total price | Save | Order |
|---|---|---|---|---|
| 1.5 x 30 Pills | $1.32 | $39.49 + Bonus - 4 Pills | - | Add to cart |
| 1.5 x 60 Pills | $0.92 | $55.29 + Bonus - 4 Pills | $24.00 | Add to cart |
| 1.5 x 90 Pills | $0.79 | $71.08 + Bonus - 7 Pills | $47.70 | Add to cart |
| 1.5 x 120 Pills | $0.72 | $86.88 + Bonus - 7 Pills | $72.00 | Add to cart |
| 1.5 x 180 Pills | $0.66 | $118.47 + Bonus - 11 Pills | $118.80 | Add to cart |
| 1.5 x 270 Pills | $0.61 | $165.85 + Bonus - 11 Pills | $191.70 | Add to cart |
| 1.5 x 360 Pills | $0.59 | $213.24 + Bonus - 11 Pills Free Trackable Delivery | $262.80 | Add to cart |
Your order will be packed safe and secure and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has a size and a look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm) and it does not disclose its contents
The tablets are aimed at reducing the ability of smooth muscle vessels to contract and to stimulate the synthesis of prostaglandin PGE2 and prostacyclin PGI2 (vasodilator and platelet aggregation inhibitor).
Product Description
The pills increase the excretion of sodium in the urine, and to a lesser extent the release of magnesium and potassium. Thus the action of diuresis becomes faster. The effect of the drug persists even in people with hypertension. The medicine operates at the level of the vessels. It decreases the contractility of the muscles of blood vessels, stimulates indapamide in blood vessels, and reduces left ventricular hypertrophy.
According to studies that had different duration-short, medium and long, it has been determined that the pills do not affect the metabolism of lipids, triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein; they do not influence the metabolism of carbohydrates, even in patients with hypertension and diabetes. If the recommended dose is exceeded, then the therapeutic effect of the components of the tablet will not be greater and the frequency of adverse reactions will increase. One should not increase the dose if the treatment is ineffective.
Safety Information
The tablets are not recommended and are contraindicated for people who have a high sensitivity to them or any other excipients. The pills are not recommended for people with severe renal insufficiency, with severe liver function disorders, with hypokalemia. It is not advised to combine medicine with lithium at a high level of its concentration in plasma may appear. They will be together with the symptoms of overdose with a salt-free diet. If you are appointed a diuretic, it is necessary to conduct a thorough study of the level of lithium in the blood.
If you take pills with the drugs mentioned above, there is a risk of gastric arrhythmia and gastric tachycardia or hypokalemia. Before taking this combination of tablets you need to check the level of potassium and correct it to a normal level if necessary. It is also necessary to control the level of plasma electrolytes. If there is hypokalemia, you need to take drugs that do not cause wave burst arrhythmia.
The best time for taking remedy is in the morning, 1 tablet (0.0015 g), without grinding, without chewing and washing with a ½ cup of water. The maximum daily dose - 1 tablet (0.0015 g).
Side Effects
A large number of negative effects (clinical or laboratory parameters are known to depend on the dose of the pill) can cause such adverse reactions as:
- Thrombocytopenia, hemolytic anemia, leukopenia, agranulocytosis;
- Dizziness (vertigo), fatigue, headache, paresthesia; fainting.
- Arrhythmia, hypotension; paroxysmal ventricular tachycardia;
- Vomiting; nausea, constipation, dry mouth; pancreatitis;
- Renal failure.
Patients with hypersensitivity who had a high predisposition to allergies and asthma, maculopapular rash; purpura; angioedema and/or urticaria, toxic epidermal necrolysis.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Viagra Professional - Advantage of Professional Viagra from usual Viagra is that it works twice longer (6 - 8 hours) and has a stronger effect. Strengthens desire, improves brightness of sexual feelings and increases duration of sexual intercourse.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
