Prometrium is used as part of hormone replacement therapy for women who underwent menopause (menopause) and did not have a hysterectomy (surgical removal of the uterus). Prometrium is also used to cause menstruation for women of childbearing age.
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Product Description
Prometrium contains Progesterone - a yellow body hormone. It is used to resume menstrual cycles in women. It penetrates into the nucleus of the cell, binding to the surface of the cells of target organs with receptors, activates DNA and enhances the formation of RNA. Progesterone promotes the transition of the mucous membrane of the uterus to the secretory phase from proliferative, creates the conditions that are necessary for implantation of a fertilized egg, relaxes the muscles of the uterus (tocolytic effect) and reduces its sensitivity to oxytocin.
Safety information
Indications:
- fibro-cystic mastopathy,
- premenstrual syndrome,
- menopause (including premature),
- premenopause,
- postmenopause - as a gestagenic component of hormone replacement therapy along with estrogens.
- hypersensitivity,
- a tendency to thrombosis,
- severe violations of the functional state of the liver,
- acute forms of thromboembolic diseases or phlebitis,
- incomplete abortion,
- vaginal bleeding of unknown origin,
- porphyria.
- allergic reactions,
- transient dizziness (1-3 hours after taking),
- drowsiness,
- menstrual cycle disorders (intermediate bleeding, shortening of the cycle).
Method of application of Prometrium and dose
Progesterone is taken orally (regardless of food intake), but also can be used topically, intramuscularly, intravaginally…The choice of dosage form and dosage regimen depends on the indications. The duration of therapy is determined by the characteristics and nature of the disease. When treating progesterone, the concentration of attention is weakened, so you should be careful while driving and going for other dangerous activities that require the quickness of psychomotor reactions.
Contraindications for use:
If absolutely necessary, it is possible to use Prometrium during pregnancy and breastfeeding according to the prescription of the doctor with established deficiency of the hormones of the yellow body. Women who are planning pregnancy in the nearest future should not use progesterone.
Side effects
- allergic reactions,
- transient dizziness (1-3 hours after taking),
- drowsiness,
- menstrual cycle disorders (intermediate bleeding, shortening of the cycle).
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