Prometrium is used as part of hormone replacement therapy for women who underwent menopause (menopause) and did not have a hysterectomy (surgical removal of the uterus). Prometrium is also used to cause menstruation for women of childbearing age.
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Product Description
Prometrium contains Progesterone - a yellow body hormone. It is used to resume menstrual cycles in women. It penetrates into the nucleus of the cell, binding to the surface of the cells of target organs with receptors, activates DNA and enhances the formation of RNA. Progesterone promotes the transition of the mucous membrane of the uterus to the secretory phase from proliferative, creates the conditions that are necessary for implantation of a fertilized egg, relaxes the muscles of the uterus (tocolytic effect) and reduces its sensitivity to oxytocin.
Safety information
Indications:
- fibro-cystic mastopathy,
- premenstrual syndrome,
- menopause (including premature),
- premenopause,
- postmenopause - as a gestagenic component of hormone replacement therapy along with estrogens.
- hypersensitivity,
- a tendency to thrombosis,
- severe violations of the functional state of the liver,
- acute forms of thromboembolic diseases or phlebitis,
- incomplete abortion,
- vaginal bleeding of unknown origin,
- porphyria.
- allergic reactions,
- transient dizziness (1-3 hours after taking),
- drowsiness,
- menstrual cycle disorders (intermediate bleeding, shortening of the cycle).
Method of application of Prometrium and dose
Progesterone is taken orally (regardless of food intake), but also can be used topically, intramuscularly, intravaginally…The choice of dosage form and dosage regimen depends on the indications. The duration of therapy is determined by the characteristics and nature of the disease. When treating progesterone, the concentration of attention is weakened, so you should be careful while driving and going for other dangerous activities that require the quickness of psychomotor reactions.
Contraindications for use:
If absolutely necessary, it is possible to use Prometrium during pregnancy and breastfeeding according to the prescription of the doctor with established deficiency of the hormones of the yellow body. Women who are planning pregnancy in the nearest future should not use progesterone.
Side effects
- allergic reactions,
- transient dizziness (1-3 hours after taking),
- drowsiness,
- menstrual cycle disorders (intermediate bleeding, shortening of the cycle).
Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
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Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Cephalexin - antibacterial agents for systemic use. Cephalosporins of the first generation. Used in the treatment of infections caused by microorganisms susceptible to cefalexin: ENT organs and respiratory tract, genitourinary system, skin and soft tissues, bone tissue and joints.
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Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.
Cardioselective beta-1 blocker. Does not have a membrane-stabilizing action and does not have an internal AGR. Has antihypertensive, anti-angiogenic and antiarrhythmic action. It is used for IHD, angina pectoris, unstable angina, myocardial infarction, arterial hypertension, hypertensive crisis, tachycardia, thyrotoxicosis.
An antimicrobial agent from the nitrofurans group, especially suitable for the treatment of urinary tract infections and prevention of infections after urologic surgery or examinations (cystoscopy, catheterization, etc.). The medicine disrupts the permeability of the cell membrane and protein synthesis in bacteria.
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A blocker of H1-histamine receptors of the first generation, derived from ethanolamine; eliminates the effects of histamine, mediated through this type of receptors. Promotes the local anaesthesia (when intaken, there is a short numbing of the mucous membranes in the mouth) - only in high doses, it blocks m-cholinergic receptors in the central nervous system, has sedative, hypnotic, antiemetic and antiparkinsonian effects. The therapeutic indications include: allergic conjunctivitis, allergic rhinitis, chronic urticaria, pruritic dermatoses, dermatographism, serum sickness.
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Sumycin - An antibiotic based on tetracycline, a brand of such pharmaceutical companies as Bristol-Myers Squibb, Apothecon, Par Pharmaceutical.
Vantin - combined preparation, based simultaneously on 2 active substances: Cefpodoxime Proxetil. It belongs to the third generation of cephalosporins. Used to treat acute otitis media, tonsilitis, pharyngitis, respiratory tract infections, such as pulmonary pneumonia and chronic bronchitis.
Atorlip-5 is a drug which purpose is to lower the level of so-called bad cholesterol in the human organism. Its amount is identified due to the blood testing. The accumulation of low-density lipoprotein can lead to atherosclerosis. As the result, arteries are getting narrow causing cardiovascular complications as strokes, heart attacks, hypertonia, and peripheral artery disease. Liver fat can be also reduced thanks to the drugs. The other benefit is that the medicine increases the level of high-density lipoprotein.
Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
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ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below: