An antimicrobial agent from the nitrofurans group, especially suitable for the treatment of urinary tract infections and prevention of infections after urologic surgery or examinations (cystoscopy, catheterization, etc.). The medicine disrupts the permeability of the cell membrane and protein synthesis in bacteria.
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Macrobid Product Description
Drug Uses
Macrobid is a drug with antimicrobial activity, a synthetic antibiotic from the class of nitrofurans, used to treat urinary tract infections.
This antibacterial agent is effective against Gram-positive and Gram-negative bacteria, such as Staphylococci, Escherichia coli, Streptococcus, Klebsiella and Citrobacter. When used in low doses, Macrobid usually exerts bacteriostatic effect on the microorganisms, while as in high doses it can exert a bactericidal effect.
The antibacterial agent Macrobid is prescribed to adults and pediatric patients (including infants, from the second month of life) for the treatment and prophylaxis of infections in the bladder, kidney and other parts of the urinary tract.
The therapeutic dose of Macrobid for the treatment of lower urinary tract infections in pediatric patients is adjusted depending on the child's weight. The daily dosage for patients in this age group is between 5 and 7 mg per kg of body weight, divided into 4 doses. The daily dose of this antibacterial agent for adults and children of 12 years and older is one Macrobid 100mg capsule every 12 hours, 7 days in a row.
Missed dose
Take the missed dose of Macrobid, as soon as you remember. But do not take it at all, if it is nearly time for your next dose of the antibiotic. Then go back to the regular dosing schedule of the antibacterial agent.
More Information
Most strains of Proteus, Pseudomonas species or Serratia species are not sensitive to Macrobid, so this antibacterial is not recommended for the treatment of urinary tract infections, caused by these microorganisms. Macrobid is not recommended for the treatment of perinephric abscesses, pyelonephritis, any systemic infections, or in prostatitis.
Storage
Antibacterial agent Macrobid should be kept in its original package to protect from moisture at controlled room temperature of 20°C to 25°C.
Macrobid Safety Infor mation
Warnings
Macrobid should be discontinued, if lung diseases of varying severity develop in the patient. Using antibacterial agent for more than 24 weeks increases the risk of such disorders, as the interstitial lung disease or scarring of the lungs, which may lead to death.
Disclaimer
All information about the treatment of urinary tract infections, provided in the review of Macrobid, is general information, provided for educational purposes. All information materials are not intended or implied to be a substitute for professional medical advice of an urologist, gynecologist or other health professional. In no event shall the online pharmacy be liable for any damages, resulting from the use or inability to use material on the antibacterial agent, contained in the review on Macrobid.
Macrobid Side Effects
Adverse effects of Macrobid are usually mild and do not require discontinuation of the antibiotic. The antibacterial agent most common causes nausea, anorexia, pancreatitis, emesis, flatulence, indigestion, sialoadenitis, headache, hair loss, itch, polyneuropathy, leukopenia or somnolence. Less commonly, the patients taking Macrobid, may notice pseudomembranous colitis, hepatitis, cholestatic jaundice, cough, shortness of breath, optic neuritis, weakness, vertigo, depression, euphoria, confusion, fever, eosinophilia, or shivering.
Being a part of the medicine Allegra - fexofenadine it is an antihistamine with a selective antagonistic activity to H1-receptors without anticholinergic and blocking alfa1-adrenergic receptors; also at fexofenadine isn't observed a sedative action and other effects from the central nervous system. The antihistaminic effect of Allegra is observed in 1 hour, reaching its maximum in 6 hours, and proceeds within 24 hours. After 28 days of taking the medicine there wasn't observed the accustoming to it.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
ED Trial Pack (2 Viagra + 2 Cialis + 2 Levitra) - a trial set consists of six tablets, for those who want to understand what medicine is better for him. Includes 6 tablets (by 2 pсs.): Viagra, Cialis and Levitra. It can be taken by people older than 18 years, in case of problems in private life related to fatigue, stress, sleep debt, slow-moving way of life and abuse of addictions.
Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Coversyl is ACE inhibitor. It eliminates arterial hypertension, by means of disturbance of formation of angiotensin 2 and stopping of its narrowing impact on arterial vessels. At long treatment the drug recovers elasticity of big vessels and hypertrophy of a left ventricle decreases. At heart failure the medicine reduces a myocardium hypertrophy.
Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Keflex – It is used for the treatment of infections of the upper respiratory tract, urogenital system, ENT organs, skin and soft tissues, bones and joints. Refers to a group of cephalosporin antibiotics of the first generation. It has an bactericidal effect, disrupts the synthesis of the cell wall of microorganisms. It is resistant enough to penicillinases of gram-positive microorganisms, It can be destroyed by beta-lactamases of gram-negative microorganisms.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
A blocker of H1-histamine receptors of the first generation, derived from ethanolamine; eliminates the effects of histamine, mediated through this type of receptors. Promotes the local anaesthesia (when intaken, there is a short numbing of the mucous membranes in the mouth) - only in high doses, it blocks m-cholinergic receptors in the central nervous system, has sedative, hypnotic, antiemetic and antiparkinsonian effects. The therapeutic indications include: allergic conjunctivitis, allergic rhinitis, chronic urticaria, pruritic dermatoses, dermatographism, serum sickness.
A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. therapeutical indications include: depressive phases of a manic-depressive psychosis, all other forms of endogenous depression (reactive and neurotic). In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses.
Sumycin - An antibiotic based on tetracycline, a brand of such pharmaceutical companies as Bristol-Myers Squibb, Apothecon, Par Pharmaceutical.
Vantin - combined preparation, based simultaneously on 2 active substances: Cefpodoxime Proxetil. It belongs to the third generation of cephalosporins. Used to treat acute otitis media, tonsilitis, pharyngitis, respiratory tract infections, such as pulmonary pneumonia and chronic bronchitis.
Gastroprotective agent, a synthetic analog of PgE1 boosts the formation of defensive slime and bicarbonate; enhances blood flow in the mucosa. It stimulates the healing of erosions, gastric and duodenal ulcers and is able to prevent their formation in some cases. It has a direct impact on the parietal cells of the abdomen, inhibits the lowest, and stimulated (by meal,pentagastrin, histamine) excretion of HCl. he drug diminishes the basal production of pepsin. The expected result occurs after 30 minutes and lasts at least 3-6 hours.
Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) enzyme, which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and effective inhibitor of cyclic guanosine monophosphate (cGMP) type 5 (PDE5) phosphodiesterase enzyme in the corpus cavernosum that induces pulmonary vascular smooth muscle cell relaxation. It replenishes reduced erectile capacity by raising blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.
ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below: