It is used for the treatment of spasticity in multiple sclerosis, strokes, TBI, meningitis, spinal diseases (infectious, degenerative, tumor and traumatic genesis), in children's cerebral palsy; alcoholism (affective disorders). Reducing the excitability of the end sections of the afferent sensitive fibers and suppressing the intermediate neurons, inhibits the mono- and polysynaptic transmission of nerve impulses; reduces the preliminary stress of the muscle spindles.
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Lioresal Product Description
Drug Uses
Lioresal is an antispastic drug, acting at the spinal level and reducing painful flexor spasms and spontaneous clonus in patients with muscle spasticity. In contrast to the centrally acting antispastic drugs, Lioresal has no sedative effect and improves the patient’s overall health.
Lioresal is prescribed to pediatric patients (newborns) and adult patients (including elderly) for relief of spasticity of voluntary muscle, caused by multiple sclerosis, cerebrovascular accidents, spinal lesions and traumatic head injury.
Usually, the treatment of spasticity is started with the lowest dose of Lioresal. The recommended initial dose for adults is 15 mg per day (three Lioresal 5mg tablets). Thereafter, the dosage of the antispastic drug is gradually increased every three days at the average by 15mg.
Typically, to achieve the desired anti-spastic effect, the sufficient daily dose is 60mg, but some patients may require a daily Lioresal dose of 100 mg.
Missed Dose
If you’ve forgotten to take a scheduled dose of Lioresal, take it as soon as possible and return to your regular dosing schedule. Do not take two doses of Lioresal at the same time or close to each other. In case it is almost time for your next dose of the antispastic agent, just wait for the proper time and skip the forgotten dose of Lioresal.
More Information
Because of high risk of renal dysfunction and higher CNS toxicity, the elderly patients should be treated with low doses of Lioresal (15 to 30 mg per day). The initial pediatric dose of Lioresal is adjusted depending on the child's body weight, and usually it makes approximately 0.3mg/kg a day. Lioresal daily dose can be gradually increased, but no more often than once a week. The maximum recommended dose of Lioresal for children is 40 to 60 mg per day.
Storage
Lioresal should be kept in a tight container with a child-resistant closure, in a warm dry place. It is strictly advised to avoid freezing or heating the tablets Lioresal. The recommended temperature for storage of antispastic agent Lioresal varies from 15°C to 30°C.
Lioresal Safety Information
Warnings
The patients with epilepsy or a history of convulsive disorder are recommended to take extreme caution while using Lioresal. Lioresal may exacerbate epileptic manifestations and deterioration of seizure control. Lioresal can be used, provided that the patient has an appropriate anticonvulsant therapy.
Lioresal may worsen the state of the patients suffering from schizophrenia, Parkinson's disease, depressive or manic disorders. Therefore, the patients with psychiatric and nervous system disorders should be careful passing the treatment of spasticity with Lioresal under thorough medical supervision.
Disclaimer
The research and clinical material, published in the review of Lioresal, is provided for understanding and information about spasticity treatment, and is not intended to replace a personal medical advice by the health care professional. The online pharmacy shall not be liable for any damages, problems and loss, arising from the use of materials of Lioresal antispastic agent.
Lioresal Side Effects
At the beginning of the treatment of spinal cord diseases with Lioresal pills, the following adverse events may appear: weakness, somnolence, muscular hypotonia, fatigue, nausea, sedation or dizziness. Typically, these adverse events occur in high doses of Lioresal, so their frequency and intensity can be managed by reducing the dosage. Lioresal causes mild adverse events which do not require withdrawal of the antispastic agent. Sometimes such adverse events as hallucinations and confusion can be observed in the elderly and the patients with cerebrovascular disorders during Lioresal therapy.
Antabuse - the medicine for treatment of alcoholism. The effect of medicine is implemented due to blockade of acetaldehydehydrogenaz which takes part in ethanol metabolism in consequence of which rises the level of acetaldehyde which causes a number of negative symptoms (including hot flashes, hyperemia of face, vomiting, tachycardia and increase in pressure). These effects arising after alcohol intake lead to development of cause-effect relations and rejections of alcohol intake. Thus, the patient has a conditioned-reflex disgust for a smell and taste of alcohol.
Brand Cialis improves erection and helps to achieve a successful sexual intercourse. It is the original medication, intended for use in adult men, who have problems with achieving and maintaining an erection. The pills start acting in 30 to 60 minutes. You can benefit from their effects for up to 36 hours. Therefore, you can take the pills on Saturday evening and enjoy a wonderful weekend, full of sex and pleasant emotions both for you and your partner. The active substance is Tadalafil.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
Arcoxia - analgesic and anti-inflammatory drug of a group of highly selective cyclooxygenase-2 inhibitors. The drug has anti-inflammatory, analgesic and antipyretic effect.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
Depakote - antiepileptic medicine, has the central myorelaxation and sedative effect. It is taken for treatment of epilepsy of various genesis, at epileptic seizures, febrile spasms at children, and character changes caused by epilepsy.
Elavil - antidepressive medicine. Renders also some analgesic, H2-histamineblocking and antiserotonin action, promotes elimination of bedwetting and reduces appetite. It is taken at Depressions (especially with anexiety, agitation and sleep disorders, including children's age, endogenous, involutional, reactive, neurotic, medicinal, at organic lesions of a brain, alcoholic abstinence), schizophrenic psychoses, mixed emotional frustration, behavior disorders, night enuresis, nervous bulimia, chronic pain syndrome.
Frumil - combined diuretic medicine which consists of AMILORIDE HYDROCHLORIDE ANHYDROUS and FRUSEMIDE which action is caused by its components; it has diuretic and hypotensive effect. Amiloride reduces egestion of K+ and Mg2+. FRUSEMIDE "looping" diuretic. The combination of components of a drug reduces a risk of development of hypopotassemia and hypomagnesiemia.
An antimalarial drug that acts on the erythrocyte forms of the pathogens of human malaria. It is effective against pathogens of malaria, resistant to other antimalarial drugs (chloroquine, proguanil, pyrimethamine, combination of pyrimethamine with sulfonamides).
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
Trimox has an active ingredient called amoxicillin. It is an antibiotic of penicillin, which fights bacteria. Trimox is used to treat many different types of infection caused by bacteria such as tonsillitis, bronchitis, pneumonia, gonorrhea and infections of the ear, nose, throat, skin or urinary tract. This remedy is sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a gastric acid reducer, called lansoprazole (Prevacid).
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
Forzest is one of the best erectile dysfunction drugs. Sildenafil Citrate, Tadalafil, Vardenafil, Avanafil, Dapoxetine, and other active components provoke a hard and stable erection. Forzest contains 20 mg of Tadalafil that relaxes blood vessels. Thanks to that the blood can easily stream to the genitals and cause enough pressure to make the penis erect. The drug can be also used to treat other diseases like pulmonary hypertension and diabetes.
Seroflo represents a family of remedies ensuring alleviation of the symptoms of ordinary asthma. The medication’s ingredients include fluticasone propionate and salmeterol xinafoate that constitute many time-tested treatments of protracted bronchitis and acute pulmonary glands disorders. The corticosteroid nature of fluticasone plus salmeterol as a long-performing beta-agonist help to eliminate asthma attacks and provide anti-inflammatory action. Patients can breathe with ease and get relieved from obstructing mucus in their airways. Seroflo works as a preventive agent and cannot terminate an asthma bout that has already begun.
Zudena is another representative of the PDE5 inhibitors ubiquitously used in contemporary urology. It is commonly used for the therapy and prevention of erectile dysfunction. The pills contain udenafil – a reverse inhibitor of the phosphodiesterase-5, which is responsible for filling the penis with blood. This active ingredient has a range of recently introduced advantages the most notable of which are more rapid absorption (30-60 minutes) and increased half-life (starting from 10 to 12 hours, which leads to a 24-hour period of activity). The medicine may be prescribed not only for symptomatic but also for a long-term treatment.
Lquin Tablet is an antibiotic medicine. It is used for the treatment of bacterial infection of the lungs, throat, airways, nose, ears, urinary tract, skin and soft tissues. It contains levofloxacin.
Meloset 3 mg tablet contains Melatonin as its active component. It is used to treat sleep disorders like insomnia, jet lag and is also helpful in regulating your sleep-wake cycle.
Dapsone is a pharmaceutical antibiotic used for the treatment of symptoms related to severe skin conditions caused by bacterial infections. It decreases the swelling, among other symptoms in skin affected by dermatitis, and leprosy (Hansen’s disease). Each tablet contains 100mg of dapsone. The generic brand for this medication is: Aczone.
Calcort is a steroid that reduces inflammation in the body.
Calcort is used to treat Duchenne muscular dystrophy in adults and children who are at least 5 years old.
Calcort is not a cure for muscular dystrophy, but this medicine may improve muscle strength and slow the progression of disability.
Calcort may also be used for purposes not listed in this medication guide.
