Antiepileptic agent; binds to the additional subunit (a2-delta protein) of the potential-dependent Ca2 + -channels in the CNS, which promotes the manifestation of analgesic and anticonvulsant action. Reduction in the frequency of seizures begins within the first week.
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Lyrica product description
An active ingredient of Lyrica is pregabalin, which has an anticonvulsant and antiepileptic effect. Corporation Pfizer synthesized pregabalin at the end of the last century. The company initially positioned Lyrica as a modern antiepileptic agent, devoid of serious side effects typical for this class of drugs, and not causing addiction. Later it turned out that Lyrica remarkably fights anxiety and relieves depression, and the area of application has naturally expanded. The mechanism of action of Lyrica has not been completely studied yet. It is known that the substance acts on the same areas of the brain as tranquilizers, but it is not clear why it causes the physical and mental excitement not peculiar to tranquilizers. In medical circles pregabalin has established itself as a drug for the treatment of epilepsy and anxiety disorders.
Lyrica safety information
During Lyrica treatment, it is necessary to evade from driving vehicles and practicing potentially dangerous activities that require a high concentration of attention and speed of psychomotor reactions.
Women of reproductive age should use reliable methods of contraception, while treatment of Lyrica. The drug is prescribed to pregnant women only if the intended benefit to the mother outweighs the risk to the fetus.
If patients with diabetes mellitus on the background of taking Lyrica increased body weight, correction of doses of hypoglycemic medicines is necessary. Treatment of the elderly can cause dizziness and drowsiness, which increases the risk of injury in the latter.
Do not administer Lyrica to patients with hypersensitivity to pregabalinum or other components of the drug. The drug is contraindicated for children under 17, women during lactation and people with impaired lactose absorption and intolerance to lactose.
Interaction with other substances
Pregabalin is metabolized to an insignificant degree in the body and practically does not bind to plasma proteins, so the pharmacokinetic interaction of Lyric with other drugs is unlikely.
The intake of Lyrica can enhance the effects of Lorazepam and ethanol. With the simultaneous use of pregabalin and oxycodone, there is an increase in impairments of the mnestic function and the basic motor functions, which are caused by the intake of oxycodone.
The drug does not affect the pharmacological effects of other anticonvulsants, as well as the effectiveness of oral contraceptives, diuretics, oral antidiabetics, and insulin.
Lyrica side effects
In evidence-based medicine, there is no evidence of the negative effect of Lyrica on the liver. The fact is that pregabalin is not processed in the liver, therefore its toxic effect on this organ is minimal. Regarding the influence of Lyrica on sexual function - there is no reliable information about the irreversible damage to the testicles and impotence caused by Lyrica. But the negative impact of Lyrica on the kidneys does not cause any doubt. Many patients complain of swollen limbs and pain in the lumbar region during treatment with pregabalin. In addition, according to a recent experiment in mice, pregabalin and its predecessors can interfere with the development of cellular bonds in the brain, which is fraught with early dementia.
Caduet consists of Amlodipine besylate and atorvastatin calcium. Caduet has a double mechanism of action; action of amlodipin as dihydropyridinic antagonist of calcium and for suppression of atorvastatin HMG-CoA reductase. It is taken for prevention of cardiovascular events at patients with hypertension, with three concurrent factors of cardiovascular risk, with cholesterol level from normal to moderately raised, without clinical manifestations of ischemic heart disease and also when according to the existing recommendations about treatment the combined use of amlodipin and low dose of atorvastatin is deemed appropriate.
Brand Cialis improves erection and helps to achieve a successful sexual intercourse. It is the original medication, intended for use in adult men, who have problems with achieving and maintaining an erection. The pills start acting in 30 to 60 minutes. You can benefit from their effects for up to 36 hours. Therefore, you can take the pills on Saturday evening and enjoy a wonderful weekend, full of sex and pleasant emotions both for you and your partner. The active substance is Tadalafil.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
Exelon drug for treatment of Alzheimer's disease with poorly and moderately expressed dementia. By the principle of action of Exelon it is the Selection inhibitor of acetylcholinesterase of a brain.
Hytrin refers to the group of pharmaceutical products intended to cure the sexual/urinary maladies and sex hormone medical preparations. Its composition includes Terazozin - a medical mean for the normalization of the prostate gland in benign hypertrophy.
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
Lquin Tablet is an antibiotic medicine. It is used for the treatment of bacterial infection of the lungs, throat, airways, nose, ears, urinary tract, skin and soft tissues. It contains levofloxacin.
Dapsone is a pharmaceutical antibiotic used for the treatment of symptoms related to severe skin conditions caused by bacterial infections. It decreases the swelling, among other symptoms in skin affected by dermatitis, and leprosy (Hansen’s disease). Each tablet contains 100mg of dapsone. The generic brand for this medication is: Aczone.