Danazol is used in endometriosis (with concomitant infertility), benign neoplasms of the breast (fibrocystic mastopathy), primary menorrhagia, premenstrual syndrome, primary premature puberty, gynecomastia.
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Danazol product description
Danazol belongs to the group of drugs intended for the treatment of sexual/urinary diseases and sex hormone preparations.
The composition includes Danazol - a means that modulates the work of the reproductive system.
Danazol inhibits the production of gonadotropic hormones (follicle-stimulating and luteotropic) by the pituitary gland. Gonadotropin deficiency slows the work of ovaries and ovulation, reduces the concentration of estrogen in the body, endometrial atrophy occurs. With endometriosis, the medication damages normal and ectopic areas; reduces the area of damaged areas and reduces pain. Under the influence of the drug, proliferation of erythrocytes, the development of immunoglobulins and autoantibodies is reduced. In case of mastopathy with fibrocystic formations, Danazol helps to reduce the size of the nodes or complete their dissolution with the elimination of pain and discomfort. By increasing the content of the C1-esterase inhibitor, Danazol helps with hereditary angioedema. Pharmacological action of the drug is reversible. In case of using the high tolerated doses, Danazol may have a weak androgenic effect and may be accompanied by anabolism.
Danazol safety information
Danazol is forbidden for people with allergies to danazol and intolerance to other capsule components. The drug is contraindicated if the patient has porphyria, glucose-galactose malabsorption, heart failure, kidney and liver, bleeding from the genital organs without establishing the cause, acute thrombosis and thromboembolic disease, lactose deficiency. Danazol is not allowed for oncological patients with androgen-dependent tumors, breast cancer. Capsules are not allowed for children under 18 years of age. It is possible to treat Danazol with liver, kidney, heart and vascular diseases, diabetes mellitus, hypertension, migraine, polycythemia, epilepsy, dyslipidemia, with persistent androgenic reactions to sex hormone therapy in the anamnesis, with caution. Caution should be taken while consuming medication in case of violation of plasma mechanisms of hemostasis and any other conditions that can worsen if the water-electrolyte balance is disturbed. It is forbidden to use Danazol for the medical care of pregnant and lactating women. During therapy, non-hormonal methods of contraception should be used.
Danazol side effects
Often, with the use of capsules, some patients may experience the following adverse reactions: seborrhea, acne, emotional lability, weight gain, hirsutism, alopecia, voice coarsening, increased appetite, menstrual irregularity, mucous hemorrhagic discharge between menstruation, amenorrhea, vaginal dryness, anxiety, changes in libido, irritation of the vaginal mucosa , hot flashes, headache, hypersensitivity to insulin, decreased glucose tolerance, increased HDL concentration, decreased thyroxine content, rash, fever, facial edema and Charter, photosensitivity, pain in the back, extremities and joints, muscle spasms, tremors, fasciculation, depression, nervousness, nausea. Infrequent use of Danazol can cause a decrease in the mammary glands, urticaria, an increase in the activity of serum transaminases. Rarely, tachycardia, pancreatitis, visual impairment, clitoral hypertrophy, fluid retention in the body, decreased spermatogenesis, inflammation of the erythematous nodes, leukopenia, skin pigmentation disorder, exfoliative dermatitis, exudative erythema multiforme, cholestatic jaundice, hypertension, palpitation, thrombotic complications, an increase in the content of red blood cells and platelets, dizziness, polycythemia, increased intracranial pressure, thrombocytopenic benign adenoma of the liver, weakness. Very rarely, Danazol therapy provokes myocardial infarction, epilepsy weighting, migraine attacks, eosinophilia, splenic peliosis, malignant tumor and liver hemorrhage, hematuria, epigastric pain, carpal tunnel syndrome, interstitial pneumonia.
Altace, which is Antihypertensive (the reducing arterial pressure) medicine, inhibitor of angiotensine transforming enzyme. Suppressing angiotensin II synthesis, narrowing a luminal occlusion also reduces its stimulating influence on effuse of aldosteron. Increases activity of a renin in plasma. The medicine also inhibits metabolism (interferes with decomposition in an organism) of bradykinin. Medicine reduces the general vascular peripheral resistance, does not change significantly a renal blood flow.
Brand Levitra – a drug from Bayer, with a basic chemical called Vardenafil, is an improved remedy for treating erectile difficulties. Operates approximately within 6-8 hours, so a man may be ready to perform sexually the whole night.
ED Trial Pack (2 Viagra + 2 Cialis + 2 Levitra) - a trial set consists of six tablets, for those who want to understand what medicine is better for him. Includes 6 tablets (by 2 pсs.): Viagra, Cialis and Levitra. It can be taken by people older than 18 years, in case of problems in private life related to fatigue, stress, sleep debt, slow-moving way of life and abuse of addictions.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Colospa - myotropic spasmolytic with selective effect on unstriated muscles of digestive tract. Eliminates a spasm, without influencing a normal peristaltics of intestines. Unlike cholinolytic medicine, Colospa does not affect at muscarinic receptor and does not cause characteristic of antispasmodics with muscarinic receptor action of side effects (feeling of dryness in a mouth, vision disorders, an urination delay) that allows for patients to take it at prostatauxe or glaucoma. Taking of Colospa is not followed by development of reflex hypotonia of intestines.
Cozaar is used to treat arterial hypertension, protect the kidneys in type 2 diabetes mellitus with proteinuria, reduce the risk of associated cardiovascular diseases, as well as lower the death rate for hypertension, hypertrophy.
Endep - tricyclic antidepressant. The mechanism of antidepressive action is connected with increase in concentration of noradrenaline in synapses and/or serotonin in CNS (decrease in return absorption). Accumulation of these neurotransmitters results from inhibition of their return capture by membranes of presynaptic neurons.
Famvir - antiviral medicine which is taken for prevention and treatment of herpes at primary infection, post-herpetic neuralgia, recurrent genital herpes. Pro-medicine; represents a 6-deoxysidiacetil analog of active antiviral agent of a penciclovir.
Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
Vermox - anthelminthic drug of a wide spectrum of action. The most effective for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Taenia solium, Echinococcus granulosus, Echinococcus multilocularis, Trichinella spiralis, Trichinella nativa, Trichinella nelsoni.
Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of ATP.
The effect of clomipramine is to inhibit the opposite neurological catching of serotonin and noradrenaline. The most crucial is the suppression of serotonin recapture. In addition, the medicine has a broad range of other pharmacological actions: alpha 1-adrenoliticheskoe, anticholinergic, antigestagen and antiserotonergic. The pill acts on the depressive disorder in general. The difference is usually observed after 2-3 weeks of therapy. Acticine also has a specific influence on obsessive-compulsive disorders.
It is a powerful tool which lowers cholesterol in the blood, strengthens blood vessels and fights parasites. Lasuna balances coronary function prevents the accumulation of cholesterol on the walls of the coronary arteries. The medicine stabilizes blood pressure levels. It regulates the level of lipids in plasma, the number of platelets in the blood, cholesterol and blood sugar and strengthens immunity. Strong antioxidant properties eliminate free radicals that cause an imbalance in the normal functioning of blood vessels, which should fully narrow and expand for their natural work.
ERYC capsules contain enteric-coated pellets of erythromycin base for oral administration.
Erythromycin is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below: