Prometrium is used as part of hormone replacement therapy for women who underwent menopause (menopause) and did not have a hysterectomy (surgical removal of the uterus). Prometrium is also used to cause menstruation for women of childbearing age.

An anti-climax combined drug which has estrogenic and gestagenic effect, restores the balance of endogenous hormones.

Estrogens regulate the development of the female reproductive system functions’ preservation, the formation of female secondary sex characteristics. The list of indications includes: vasomotor symptoms associated with estrogen deficiency in the body, osteoporosis associated with estrogen deficiency, atrophic urethritis and atrophic vaginitis.