Albenza - anthelmintic agent which is active concerning adult individuals and larval forms. Albendazole influences polymerization of β-tubulin, which stops it. As a result, occurs violation of formation of microtubules in intestines of helminths, the ability of vermis to acquire glucose is suppressed. It is blocked the normal intracellular migration of organellas, and it is prevented the synthesis of ATP in their muscular tissue. Creation of therapeutic concentration of albendaloze leads to death of helminths. Medicine causes death of nematodes (Necator americanus, Strongyloides stercoralis, Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Cutaneous Larva Migrans, Ancylostoma duodenale), cestode (pig, bull and dwarf tapeworm), trematode (Clonorchis sinensis, Opisthorchis viverrini), elementary (Lamblia).
An anthelmintic broad-spectrum drug; most effective with enterobioze and trihozefaleze. Causes irreversible violation of glucose utilization, depletes the glycogen stores in the tissues of worms, inhibits the synthesis of cellular tubulin and also inhibits the ATP synthesis.
Vermox - anthelminthic drug of a wide spectrum of action. The most effective for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Taenia solium, Echinococcus granulosus, Echinococcus multilocularis, Trichinella spiralis, Trichinella nativa, Trichinella nelsoni.
Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of ATP.