Antiepileptic agent. The use of Lamictal reduces the pathological activity of neurons without inhibiting their function. Stabilizes the neuronal membranes by affecting Na + channels, blocks excessive release of excitatory amino acids (mainly glutamate), without reducing its normal release.
The drug is a prodrug and is activated in the acidic environment of the secretory tubules in the parietal cells. It reduces basal and stimulated secretion regardless of the nature of the stimulus. Prescribed in case of erosive ulcerative diseases of the gastrointestinal tract and eradication of Helicobacter pylori in infected patients with gastric and duodenal ulcer.